“The disease led to the crisis, which seriously influences the health of a human and the global economy. Due to the novelty of this virus, no specific medications and vaccines exist. Consequently, it is necessary to urgently develop efficient vaccines against it. We held a pilot test of a purified inactivated vaccine against coronavirus, which induced specific for it neutralizing antibodies of mice, rats, and non-human monkeys,” the message said.
The scientists noted that developed antibodies neutralized 10 representative strains of coronavirus; it shows that they may neutralize other strains of the virus circulating all over the world.
“The Immunization by two different doses (3 ugs or 6 ugs per dose) provided a partial of complete protection of the macaques against coronavirus, consequently, without antibody-dependent strengthen of infection. The systematic evaluation with the help of the monitoring of clinical features, hematological or biochemical index and histopathological analysis of the macaques shows that it is safe,” the message said.
It will allow accelerating the clinical trial of the vaccine on people.
As we reported, Director of Wuhan Institute of Virology Yuan Zhiming stated that the information that the virus escaped from Wuhan Institute is not corroborated by evidence.