Israel to be first in world to test oral medications against Covid-19

Source : 112 Ukraine

According to a manufacturer, oral vaccine advantages go beyond safety and efficacy, as it tend to have fewer side effects
15:33, 22 July 2021

Drugs against Covid-19
Open source

Oramed’s daughter company Oravax Medical is preparing to begin clinical trials of its new oral Covid-19 vaccine at Tel Aviv Sourasky Medical Center. This was stated by Oramed Pharmaceuticals CEO Nadav Kidron, as The Jerusalem Post reports.

“The protocol for the inaugural Phase I/II trial that the company hopes to move forward with at Sourasky would involve 24 volunteers who have not yet been inoculated with another vaccine. Half of the group would take one capsule and the other two. There is no placebo group because the goal is to measure the level of antibodies and other immunity indicators," Kidron explained.

"The new Oravax vaccine candidate targets three structural proteins of the novel coronavirus, as opposed to the single spike protein targeted via the current Moderna and Pfizer vaccines. Thus, it should be much more resistant to COVID-19 variants," the statement reads.

Related: Pfizer vaccine creates 10 times higher antibody levels compared to CoronaVac, - study

According to Nadav Kidron, the advantages of an oral vaccine go beyond safety and efficacy, as oral medications tend to have fewer side effects.
In addition, the vaccine can be shipped at refrigerator temperatures and even stored at room temperature, “making it logistically easier to get it anywhere around the world.”
Finally, an oral vaccine would not require professional administration.

As it was reported earlier, American pharmaceutical company Moderna intends to create vaccines against other viruses, including HIV.

Related: EMA starts reviewing French COVID-19 vaccine

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