According to the message, the bus with Coptic Christians was targeted on the way towards the Monastery of St Samuel the Confessor in Minya province, about 220km (140 miles) south Cairo.
The agency reports that at least 23 people were killed in the incident, another 25 got wounded.
At the same time, it is noted that Copts are being repeatedly attacked by militants lately. Thus, 46 people were left dead after suicide bombings at churches in April.
It is noteworthy that medical sources and witnesses say that the number of victims and injured as a result of shooting is higher, claiming that 26 were killed, another 26 wounded, Reuters reported.
Earlier explosions occurred near Coptic church in Tanta city of Egypt in April and was followed by another hit in front of Saint Mark's church in Alexandria. ISIS terrorists took responsibility for the attacks.