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Gene linked to doubling risk of Covid-19 death found

Source : 112 Ukraine

The high-risk genetic variant is in a chromosome region that is also tied to double the risk of death in Covid-19 patients under age 60
23:28, 5 November 2021

Open source

British scientists have identified a version of a gene that may be associated with double the risk of lung failure from Covid-19. The research is published in the scientific journal Nature Genetics.

The high-risk genetic variant is in a chromosome region that is also tied to double the risk of death in Covid-19 patients under age 60.

Related: Booster dose of Covid-19 vaccine to be available for Ukrainians after 50% of them vaccinated

Around 60% of people with South Asian ancestry carry the high-risk version of the gene and the discovery may partly explain the high number of deaths seen in some British communities, and the devastation wrought by Covid-19 in the Indian subcontinent.

The scientists found the increased risk comes from a gene that regulates activity of other genes, including one called LZTFL1 involved in the response of lung cells to viruses.

As a result, the gene variant could inhibit proper response to the virus among cells lining airways and the lungs.

However, LZTFL1 does not affect the immune system that makes antibodies to fight off infections, researchers said, adding that people carrying the variant should respond normally to vaccines.

Related: 26,488 people contracted Covid in Ukraine over 24 hours

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Система Orphus

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