Russia is going to host clinical tests of the combination of Sputnik Light and AstraZeneca vaccines. Russia's Healthcare Ministry issued the respective license, RIA Novosti reports.
150 volunteers will participate in the research, which is supposed to be over in early March 2022.
Earlier, scientists from the Oxford University reached the conclusion that combining of Pfizer and AstraZeneca vaccines gives a powerful immune response.
The study, called Com-COV, compared mixed two-dose schedules of Pfizer and AstraZeneca vaccines and found that in any combination, they produced high concentrations of antibodies against the coronavirus spike protein. The data provides support for the decision of some European countries that have started offering alternatives to AstraZeneca as a second shot after the vaccine was linked to rare blood clots.
The highest antibody response was seen in people receiving two doses of Pfizer vaccine, with both mixed schedules producing better responses than two doses of AstraZeneca vaccine. An AstraZeneca shot followed by Pfizer produced the best T-cell responses, and also a higher antibody response than Pfizer followed by AstraZeneca. The results were for combinations of vaccines given at four-week intervals to 830 participants.