"We don't have the means to combat the violence of the regime against the demonstrators. They have the weapons, they have the force, so yes, for the moment it seems that we have lost," she told the paper.
"Our strategy is to better organise ourselves, to put the regime under constant pressure, until the moment when people will once again be ready to go back on to the streets, perhaps in spring," she added.
Belarus was gripped by months of unprecedented anti-government demonstrations that erupted after a disputed presidential election last August which saw Lukashenko claim a sixth term in office.
His opponents say the polls were rigged and that political novice Tsikhanouskaya, who ran in place of her jailed husband, was the true winner.
But Belarusian security forces unleashed a harsh crackdown against the protests, detaining demonstrators and pushing opposition leaders into exile.