Michael's manager, Michael Lippman, says the cause of death was heart failure.
"It is with great sadness that we can confirm our beloved son, brother and friend George passed away peacefully at home over the Christmas period," Michael's family said in a statement released by Thames Valley Police.
"The family would ask that their privacy be respected at this difficult and emotional time. There will be no further comment at this stage."
Big names from the world of entertainment have paid tribute to him after hearing about his death, which comes in a year that has seen the music industry lose some of its biggest stars including Prince, David Bowie, Leonard Cohen, Sir Elton John, Madonna, Duran Duran, etc.
George Michael sold more than 100 million albums throughout a career spanning almost four decades.