"This is an act of aggression, on an absolutely made-up pretext," Lavrov told a news conference in Tashkent, Uzbekistan. "It reminds me of the situation in 2003 when the United States and Britain, along with some of their allies, attacked Iraq."
US authorities did not provide any facts confirming the chemical attack in Idlib, he stressed.
Lavrov said Russia would demand Washington explain why it conducted the strikes.
"I hope this provocation will not lead to irreparable damage (to U.S.-Russian ties)," Lavrov added.
Earlier it was reported that U.S. landed a missile strike on Syrian army. It was in America’s vital security interest, according to Trump.